Hi, Dr. Warner here –
The pain of arthritis is very common. In fact, this is one of the most common reasons for people to see a doctor and certainly one of the most common reasons to seek disability compensation. There is no cure for arthritis at this time, but there are a number of medications that help to treat symptoms. However, most medications have side effects and often cannot be used for arthritis pain.
There are a variety of natural supplements that can be taken for arthritis pain, and most have decent science behind their use. One should remember, however, that supplements or medication work best to treat arthritis pain when paired with a program for weight loss and exercise, too. Low-impact aerobic exercise is one of the best ways to treat and beat the pain of arthritis.
There is an intriguing supplement on the market in Europe called Piascledine that is derived from avocado and soy. The supplement concentrates the active ingredient considered crucial for the control of arthritic pain and has been tested in placebo-controlled trials in France by the company that makes it. The Cochrane Collaboration, an independent science group, has evaluated these studies.
Basically, Piascledine has “moderate to high” evidence that it works in the short-term to relieve arthritis pain. This is good news as this is a natural product with little to no side effect profile. A more long-term study of three years found little difference in pain control between the supplement and placebo. A review study in 2008 found that the use of the avocado-soybean oil supplement reduced and even stopped the need to use NSAIDs (anti-inflammatory pills).
The French company that makes Piascledine, Laboratoires Expanscience, sells this product in 46 countries but not in the USA yet. The French experience has demonstrated the safety of the supplement over a 15 year span of use in that country.
The avocado combination provides anti-inflammatory activity and also has been shown to build up cartilage in the laboratory. The product is unsaponifiable. The unsaponifiable and anti-inflammatory product has shown a decrease in destruction of the joints over time, as examined at the University of Arizona.
According to the Arthritis Foundation, the supplement blocks pro-inflammatory substances, can help to rebuild cartilage cells, and also prevents the deterioration of the synovial (or joint) lining. Typically, the supplement works better than simply eating the vegetables as the ingredient is concentrated for you that way. The dosage ranges from 300 to 600mg per day.
The product is derived from the unsaponifiable part of the oil of the vegetable. This is a tiny fraction of the overall mass of the soybean and the avocado. The amount of avocados and soybeans that would need to be consumed to equal the unsaponifiable dose in the supplement is too large to recommend a dietary source for this substance.
This product is another natural remedy with a good side effect profile that has been found to be an effective way to treat the pain of arthritis. You should check with your doctor to make sure it will not interfere with any current supplements of medications prior to trying this product.
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Meredith Warner, MD