Top Longevity Supplements For Slowing Down Aging
Posted on Aug 10, 2022

We don’t believe in the traditional view of aging. Yes, we all get older, but that doesn’t mean anyone has to stop doing what they love to do because of it. Most of what we consider inevitable with aging is actually self-induced and we have the power to make things better for ourselves.  

There are a number of things that society as a whole has accepted to be true when it comes to getting older, and you may find yourself feeling similar anxieties or worry about what the future brings. But, you’re in more control than you think. We don’t practice agism and we don’t believe that you should either.  

When Dr. Warner founded Well Theory, she did so to empower her patients and others to improve their health on their own terms, and allow their bodies to heal naturally.

Her latest Longevity Series is a testament to this thinking. It includes three incredible supplements - Berberine, Resveratrol, and NMN.

What To Expect With Berberine

Berberine HCl, or Berberis aristata, is the first in our Longevity Series line-up.

Berberine activates adenosine monophosphate-activated protein kinase (AMPK) production, which acts as an energy sensor and helps you achieve energy homeostasis, which helps to improve your cells overall health and reduces signs of aging at the cellular level.

Perhaps the most unique aspect of this Berberine supplement, is its ability to regulate blood glucose levels and raise insulin sensitivity as well, if not better than diabetic drug Metformin. We would never seek to replace a pharmaceutical industry’s product if your physician has recommended it.

However, we are extremely excited about this natural substance found in barks of plants. Insulin sensitivity and proper function helps convert glucose into energy and allows it to be processed more efficiently. Insulin allows glucose to be pulled out of the bloodstream and put into cells where it is needed or may be processed for storage. Without a good insulin response, hyperglycemia results. Too much hyperglycemia leads to the formation of advanced glycation end products; this is essentially toasting your insides.

Berberine’s ability to improve energy levels also contributes to its amazing improvements on your metabolic health. Metabolic health is measured with five markers:

  • Blood sugar levels
  • Blood pressure
  • HDL Cholesterol
  • Triglycerides
  • Waist circumference

Berberine is able to improve on all five of these markers, making it a powerful supplement when it comes to improving metabolic health.

Resveratrol and AMPK Activation

Resveratrol is a powerful antioxidant supplement, commonly found in the skin of grapes as well as red wine. It may also be found in the skins of peanuts and in Japanese knotweed.  

Like Berberine, Resveratrol boosts AMPK activation, contributing to increased energy levels and improving mitochondrial health. As an energy sensor, AMPK can help your cells achieve homeostasis.

Resveratrol also improves Sirtuin protein activity which also improves mitochondrial function - increasing insulin sensitivity and stabilizing blood glucose levels. The Sirtuins are heavily involved in DNA repair and maintenance as well.

Because Resveratrol works as an antioxidant, it helps to neutralize free radicals that can cause damage at the cellular level. When free radicals are neutralized, your oxidative stress levels decrease as well - helping you fight signs of aging and preventing disease.

Another benefit to this antioxidant is that less free radicals means less chronic inflammation. When you lower your chronic inflammation you can relieve pain and prevent degenerative diseases like arthritis.

If you’re concerned with your cardiovascular health, Resveratrol can also lower LDL, while raising HDL cholesterol levels, reducing your risk for cardiovascular disease.

Increase NAD+ Levels With NMN

Nicotinamide mononucleotide, or NMN, is a precursor molecule for nicotinamide adenine dinucleotide, or NAD+, a vital molecule for your cellular health. As you age, your natural levels of NAD+ decline, and without NAD+ the aging process increases rapidly.

When you supplement with NMN to increase your NAD+ levels, you’re helping reverse signs of aging at the cellular level by improving mitochondrial function and reducing oxidative stress.

Oxidative stress can impact you in the short term and long term. In the moment, it creates fatigue, inflammation, and more - while in the long term it leads to noncommunicable diseases like dementia, arthritis and cancer.

NAD+ works to repair damaged DNA caused by free radicals that increase oxidative stress.

NMN can also improve your aerobic capacity during exercise. It also helps speed up muscle recovery and strength, making an active lifestyle more achievable. NAD is a mandatory shuttle molecule for the transfer of electrons (energy) from the Kreb’s cycle to the electron transport chain. Science is cool.